Answer
$$\frac{1}{4} \tan (4 x+9)+C$$
Work Step by Step
Given $$ \int \sec ^{2}(4 x+9) d x$$
Let
$$u=4 x+9 \ \ \ \ \Rightarrow \ \ \ du =4dx $$
\begin{aligned} \int \sec ^{2}(4 x+9) d x &=\frac{1}{4} \int \sec ^{2} u d u \\ &=\frac{1}{4} \tan u+C \\
&=\frac{1}{4} \tan (4 x+9)+C \end{aligned}