Answer
$-9x^{3}y^{4}$
Work Step by Step
Using the laws of exponents, the given expression, $
\dfrac{144x^5y^5}{-16x^2y}
,$ simplifies to
\begin{array}{l}\require{cancel}
\dfrac{\cancel{-16}\cdot(-9)x^{5-2}y^{5-1}}{\cancel{-16}}
\\\\=
-9x^{3}y^{4}
.\end{array}
