Answer
$\dfrac{1-4a}{4a+1}$
Work Step by Step
The given expression, $
\dfrac{a^{-1}-4}{4+a^{-1}}
,$ simplifies to
\begin{array}{l}\require{cancel}
\dfrac{\dfrac{1}{a^1}-4}{4+\dfrac{1}{a^1}}
\\\\=
\dfrac{\dfrac{1-4a}{a}}{\dfrac{4a+1}{a}}
\\\\=
\dfrac{\dfrac{1-4a}{\cancel{a}}}{\dfrac{4a+1}{\cancel{a}}}
\\\\=
\dfrac{1-4a}{4a+1}
.\end{array}