Answer
$\dfrac{1}{x^{20}y^{15}}$
Work Step by Step
Using laws of exponents, the given expression simplifies to
\begin{align*}
&
\left( \dfrac{x^4}{y^{-3}} \right)^{-5}
\\\\&=
\dfrac{x^{4(-5)}}{y^{-3(-5)}}
\\\\&=
\dfrac{x^{-20}}{y^{15}}
\\\\&=
\dfrac{1}{x^{20}y^{15}}
.\end{align*}