Answer
$$ \frac{-1}{r^3}\mathbf{r}$$
Work Step by Step
Since $$F(r)= \frac{1}{r},\ \ \ \ \ \ \ \ F'(r) = \frac{-1}{r^2} $$
Then
\begin{align*}
\nabla f &=F^{\prime}(r) e_{\mathbf{r}}\\
&= \frac{-1}{r^2}e_{\mathbf{r}}\\
&= \frac{-1}{r^2}\frac{\mathbf{r}}{r}\\
&=\frac{-1}{r^3}\mathbf{r}
\end{align*}