Answer
$$-\frac{2xy+z^2}{y^2+2xz}$$
Work Step by Step
Given $$x^{2} y+y^{2} z+x z^{2}=10$$
Consider $$F(x,y,z)=x^{2} y+y^{2} z+x z^{2}=10 $$
Then
\begin{align*}
F_x&= 2xy+z^2\\
F_z&= y^2+2xz
\end{align*}
Then
\begin{align*}
\frac{\partial z}{\partial x}&=-\frac{F_{x}}{F_{z}}\\
&=-\frac{2xy+z^2}{y^2+2xz}
\end{align*}