Answer
$(4x-5y)^{2}$
Work Step by Step
$16x^{2}-40xy+25y^2$
$\qquad$...recognize a perfect square trinomial.
$(A\pm B)^{2}=A^{2}\pm 2AB+B^{2}$; $A=4x,\ B=5y$
$=(4x-5y)^{2}$
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