Answer
The derivative is $\frac{1-x^2}{(1+x^2)^2}$
Work Step by Step
Using the quotient rule: $f'(x)=(\frac{u(x)}{v(x)})'=\frac{u'(x)v(x)-v'(x)u(x)}{(v(x))^2}$
$u(x)=x; u'(x)=1$
$v(x)=x^2+1 ;v'(x)=2x$
$f'(x)=\frac{(1)(x^2+1)-(x)(2x)}{(x^2+1)^2}=\frac{1-x^2}{(1+x^2)^2}$