Answer
$\frac{-x^{8}}{4y^{30}}$
Work Step by Step
$\frac{-5x^6y^{-10}}{20x^{-2}y^{20}}=\frac{-x^{6+2}}{4y^{20+10}}=\frac{-x^{8}}{4y^{30}}$
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