Answer
$(p+5q)(p^2-5pq+25q^2)$
Work Step by Step
Using $a^3\pm b^3=(a\pm b)(a^2\mp ab+b^2)$, or the factoring of the sum/difference of two cubes, then,
\begin{array}{l}
p^3+125q^3
\\=
(p+5q)[(p)^2-(p)(5q)+(5q)^2)
\\=
(p+5q)(p^2-5pq+25q^2)
.\end{array}