Answer
$(x+2y-3)(x+2y+3)$
Work Step by Step
Using $a^2-b^2=(a+b)(a-b)$ or the factoring of the difference of two squares, then,
\begin{array}{l}
(x+2y)^2-9
\\=
[(x+2y)-3][(x+2y)+3]
\\=
(x+2y-3)(x+2y+3)
.\end{array}
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