Answer
$4(4x+5)(4x-5)$
Work Step by Step
Factoring the $GCF=
4
$ results to $
4(16x^2-25)
$. Using $a^2-b^2=(a+b)(a-b)$ or the factoring of the difference of two squares, then,
\begin{array}{l}
4(16x^2-25)
\\=
4(4x+5)(4x-5)
.\end{array}