Answer
$-2$
Work Step by Step
We know that for a matrix
\[
\left[\begin{array}{rr}
a & b \\
c &d \\
\end{array} \right]
\]
the determinant is $D=ad-bc.$
Hence, here we have
$D=(-4\cdot3)-[2\cdot(-5)]\\
D=-12-(-10)\\
D=-12+10\\
D=-2$