Answer
$-78$
Work Step by Step
We are given: $x=-1$, $y=2$, $z=-3$
We take into account the order of operations:
Parenthesis, Exponents, Multiplication/Division, Addition/Subtraction
Thus, we have:
$$(3x+5)(2y-1)(5z+2)=(3(-1)+5)(2(2)-1)(5(-3)+2)\\
=(2)(3)(-13)=-78
.$$