Answer
$60$
Work Step by Step
We are given: $x=-3$, $y=4$, $z=6$
We take into account the order of operations:
Parenthesis, Exponents, Multiplication/Division, Addition/Subtraction
Thus, we have:$$ (2x+3y)(y+z)=(2(-3)+3*4)(4+6)\\
=(-6+12)10=6*10=60
.$$
