Answer
$-100.$
Work Step by Step
We know that for a matrix
\[
\left[\begin{array}{rrr}
a & b & c \\
d &e & f \\
g &h & i \\
\end{array} \right]
\]
the determinant, $D=a(ei-fh)-b(di-fg)+c(dh-eg).$
Hence here $D=2(0\cdot0-1\cdot6)-1(5\cdot0-1\cdot2)+(-3)(5\cdot6-0\cdot2)=2(-6)-1(-2)+(-3)(30)=-12+2-90=-100.$