Answer
$-19x^2+8x $
Work Step by Step
We remove the parentheses, distribute, and then add the products as follows
$$
3x(x- 4) + 2x(1 - 5x) - 6x(2x - 3)\\
=3x^2- 12x + 2x - 10x^2 - 12x^2+18x\\
=-19x^2+8x
.$$
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