Answer
$x=-4$
Work Step by Step
Since $\left(\frac{1}{5}\right)=5^{-1}$, then the equation becomes:
\begin{align*}5^{x+3}=5^{-1}\end{align*}
The base is the same on the 2 sides of the equation (and it is not 1), hence they will be equal if the exponents are equal.
Thus,
\begin{align*}
x+3&=-1\\
x&=-1-3\\
x&=-4
\end{align*}