Answer
$$y'' = -y^{-3}$$
Work Step by Step
Given$$x^{2}+y^{2}=1 $$
We differentiate with respect to $x$
\begin{align*}
2x+2yy'&=0\\
y'&=\frac{-x}{y}
\end{align*}
and
\begin{align*}
y''&= \frac{-y+xy'}{y^2}\\
&= \frac{-y+x\frac{-x}{y}}{y^2}\\
&= -\frac{x^2+y^2}{y^3} \\
& = -\frac{-1}{y^3} \\
& = -y^{-3}
\end{align*}