Answer
$\left( \dfrac{x}{5}-\dfrac{y}{3} \right)\left( \dfrac{x}{5}+\dfrac{y}{3} \right)
$
Work Step by Step
Using $a^2-b^2=(a+b)(a-b)$ or the factoring of the sum of 2 squares, then,
\begin{array}{l}
\dfrac{x^2}{25}-\dfrac{y^2}{9}
\\\\=
\left( \dfrac{x}{5}-\dfrac{y}{3} \right)\left( \dfrac{x}{5}+\dfrac{y}{3} \right)
.\end{array}