Answer
Vertex: $(-3,1)$.
Axis of symmetry: $x=-3$
Work Step by Step
The quadratic function in the form $y=a(x-h)^2+k$ has the vertex $(h,k)$ and the axis of symmetry $x=h$.
Given: $$f(x)=-4(x+3)^2+1.$$ Rewrite as:
$$y=-4(x-(-3)^2+1.$$ Therefore $h=-3$, $k=1$.
The vertex is: $$(h,k)=(-3,1).$$ The axis of symmetry is: $$x=-3.$$