Answer
$-18-13i$
Work Step by Step
$(-2+5i)(-1+4i)\qquad$ ...use the FOIL method.
$=(-2)(-1)+(-2)(4i)+(5i)(-1)+(5i)(4i)\qquad$ ...simplify.
$=2-8i-5i+20i^{2}\qquad$ ...simplify. ($i^{2}=-1$)
$=2-8i-5i+-20\qquad$ ...add like terms.
$=-18-13i$