Circe
Circe is the main character of the story, which is told from her point of view. She is born without her parents' beauty and power and is looked down upon by her family her entire life. Circe soon begins to realize that she despises gods and divinity. The book tells her story of isolation, determination and finally self-acceptance.
Odysseus
Despite appearing only half-way through the book, the character of Odysseus plays a major part. He becomes Circe's lover and with him she has a son Telegonus. He is portrayed as a determined hero who is, later in his life, refusing to accept that the days of his glory had passed.
Helios
Helios is the sun god and Circe's father who is always looking down on her as his failure. He is cruel and selfish, and is ready to sacrifice his own blood if necessary for his selfish purposes.
Daedalus
Daedalus appears as a character early in the book. He is describes as best among the mortals, who doesn't flinch in presence of gods. He is also one of Circe's first loves.
Pasiphaë
Pasiphaë is Circe's cruel sister who enjoys humiliating and teasing her for her appearance and voice. She becomes a wife to Zeus's son Minos and gives birth to Minotaur. Circe aids her in the birth of the beast, and during that time discovers that her sister isn't so much different from herself, being isolated and humiliated by their family in her own way.
Hermes
Hermes is a trickster Olympian who fills Circe's loneliness in the first decades of her isolation on her island. She soon finds his ways and his presence distasteful.
Telegonus
Telegonus is Circe's and Odysseus's son. Circe raises him so that he become naive to the world, hiding the truth about cruelty and darkness of it from him. As he grows up, he is determined to meet his father, ending up killing him with the poisonous spear Circe made for his protection. His dream of seeing the world is fulfilled when Athena become his patron, so that he can continue his father's glory.
Penelope
Penelope is Odysseus mortal wife and Telemachus's mother who has wisdom that challenges Circe. They become friends after Circe shelter her and her son from Athena, and she follows in Circe's footsteps in witchcraft.
Telemachus
Telemachus is Odysseus's and Penelope's son. He refuses to follow in his father's footsteps, the heroic life of glory doesn't interest him. He becomes Circe's partner at the end.