Answer
Steroid hormones use direct gene activation mechanisms to trigger changes in the cells. Steroid hormones are lipid soluble, so they can diffuse through the plasma membrane of the target cells. After entering the cell, they go to the nucleus and bind to specific hormone receptors and form the hormone-receptor complex. This complex then binds to specific sites on the cell's DNA. This activates certain genes, which transcribe the mRNA. This mRNA is translated in the cytoplasm, which results in synthesis of new proteins.
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