Answer
False
Work Step by Step
To determine whether each pair of fractions is equivalent, we can multiply $\frac{3}{8}$ by a factor of $\frac{2}{2}(=1)$ to ensure that both fractions have a denominator of 16.
$\frac{3}{8}\times\frac{2}{2}=\frac{3\times2}{8\times2}=\frac{6}{16}\ne\frac{5}{16}$