Answer
$(3\frac{7}{8},-3)$
Work Step by Step
Use the midpoint formula. Substitute the given values.
$M=(\frac{x_1+x_2}{2},\frac{y_1+y_2}{2})=(\frac{5\frac{1}{2}+2\frac{1}{4}}{2},\frac{-4\frac{3}{4}+(-1\frac{1}{4})}{2})=(\frac{7\frac{3}{4}}{2},\frac{-6}{2})=(3\frac{7}{8},-3)$