Answer
$-480$
Work Step by Step
We know that for a matrix
\[
\left[\begin{array}{rrr}
a & b & c \\
d &e & f \\
g &h & i \\
\end{array} \right]
\]
the determinant is $D=a(ei-fh)-b(di-fg)+c(dh-eg).$
Hence here $D=-2(15\cdot7-3\cdot-1)-6(8\cdot7-3\cdot4)+0(8\cdot-1-15\cdot4)=-2(108)-6(44)+0(-68)=-480.$