Human Anatomy & Physiology (9th Edition)

Published by Pearson
ISBN 10: 0321743261
ISBN 13: 978-0-32174-326-8

Chapter 2 - Chemistry Comes Alive - Review Questions - Page 59: 34

Answer

Molecular chaperones help proteins achieve their functional three-dimensional structure by preventing premature or incorrect folding, aiding in the folding process, translocating proteins and metal ions across membranes, promoting breakdown of damaged proteins, and helping trigger the immune response to diseased cells in the body.

Work Step by Step

All cells contain a class of globular proteins called molecular chaperones. Although its amino acid sequence determines the precise way a protein folds, the folding process also requires the help of molecular chaperones to ensure that the folding is quick and accurate. Molecular chaperones can associate with a broad range of “client” proteins, allowing them to perform a dizzying array of jobs.
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