Human Anatomy & Physiology (9th Edition)

Published by Pearson
ISBN 10: 0321743261
ISBN 13: 978-0-32174-326-8

Chapter 2 - Chemistry Comes Alive - Review Questions - Page 59: 33

Answer

First, the substrate binds to the enzyme’s active site, temporarily forming an enzyme-substrate complex. Then, the enzyme-substrate complex undergoes internal rearrangements that forms the product. Finally, the enzyme releases the product(s) of the reaction.

Work Step by Step

The substrate is the substance an enzyme acts on, if it has reached the activation energy. Substrate binding causes the active site to change shape so that the substrate and the active site fit together precisely, and in an orientation that favors reaction. The enzyme then acts on the substrate and releases it as a new product. The enzyme itself is not changed in this process, so it can continue acting on new substrates.
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