Answer
$x=-4$
Work Step by Step
Re-write the given equation as: $3^{-x}=3^4$ $(Because: \ 81=3^4)$
Use the rule power rule: $a^p=a^q$ .
We can see that the base $a=3$ is the same on both sides of the equation.
So, the exponents will also be equal.
This implies that $p=q$
Therefore, $3^{-x}=3^{4} \implies x=-4$