Answer
$$\frac{1}{2} \sec (4x) \tan (4x)+\frac{1}{2} \ln |\sec (4x)+\tan (4x)|+C$$
Work Step by Step
Since
$$\int \sec ^{3} u d u=\frac{1}{2} \sec u \tan u+\frac{1}{2} \ln |\sec u+\tan u|+C$$
Then
\begin{align*}
\int \sec ^{3}(4 x) d x&=\frac{1}{2} \sec (4x) \tan (4x)+\frac{1}{2} \ln |\sec (4x)+\tan (4x)|+C
\end{align*}