Answer
$-45$
Work Step by Step
Using the formula $$
\iint_{\mathcal{R}} C d A=C \cdot \operatorname{Area}(\mathcal{R})
$$
We have
$$
\iint_{\mathcal{R}} -5 d A=(-5)(5-2)(7-4)=-5(3)(3)=-45.
$$
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