Answer
$3\times 10^{24}.$
Work Step by Step
By subtracting the exponents and dividing the like terms, we have
$$
\frac{4.5 \times 10^{16}}{1.5\times 10^{-8}}= \frac{4.5 }{1.5 }\times 10^{16-(-8)}\\ =3\times 10^{24}.
$$
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