Answer
$6y^{50}\sqrt{2}$
Work Step by Step
Getting the perfect factors and then extracting its root, the simplified form of the given expression, $
\sqrt{72y^{100}}
,$ is
\begin{array}{l}\require{cancel}
\sqrt{36y^{100}\cdot2}
\\\\=
\sqrt{(6y^{50})^2\cdot2}
\\\\=
6y^{50}\sqrt{2}
.\end{array}