Answer
$8$
Work Step by Step
$\sqrt[n] {a^n}=|a|$ if $n$ is even
$16=2^4$, so $\sqrt[4]{16}=\sqrt[4]{2^4}=|2|=2$.
Then $(\sqrt[4]{16})^3=2^3=8.$
Thus $16^{\frac{3}{4}}=(\sqrt[4]{16})^3=2^3=8.$
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