Answer
$x = -4$
Work Step by Step
$3^{x} = \frac{1}{81}$
$3^{x} = 81^{-1}$
$3^{x} = 3^{-4}$
$x = -4$
Check:
$=3^{-4}$
$= \frac{1}{3^{4}}$
$= \frac{1}{3^{4}}$
$= \frac{1}{81}$
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