Answer
$\lt -1, -3 \gt $
Work Step by Step
Let us suppose that $u$ and $v$ are the two vectors:
$u=\lt 5-1, 2-6 \gt =\lt 4, -4 \gt $
and $v=\lt 9-4, 4-5 \gt =\lt 5, -1 \gt $
Thus, $u-v=\lt 4, -4 \gt - \lt 5, -1 \gt= \lt -1, -3 \gt $