Answer
See below
Work Step by Step
We are given: $f(x)=-3x^5+x^3-6x^2+2x+4$ where $x=-4$
Rewrite as: $f(x)=(x+3)q(x)+r(x)$
Since the degree must be smaller than that of $x+3$, $r(x)$ has a degree of $0$.
Substitute $-3$ for $x$:
$f(-3)=(-3+3)q(x)+r\\
\rightarrow f(-3)=r$
We can see that $f(-3)=646$