Answer
Both the substitution and elimination methods get rid of one variable. The substitution method would be better if one variable is alone on one side of the equation.
Work Step by Step
An example of when the substitution method would be better is for the following system of equations.
$y=2x-3$
$2x+5y=17$
Y is on one side (by itself) in the first equation, so we can substitute $2x-3$ into the other equation.