Head On may refer to:
Film and television- Head On (1980 film), a Canadian drama film
- Head On (1998 film), an Australian LGBT-related romantic drama film
- Head-On (film), a 2004 German-Turkish drama film
- Head On, a fictional film in the Entourage universe
- Head On (novel), a 2018 novel by John Scalzi
- Head On, a 2007 autobiography by Ian Botham
- Head-on, a 1994 autobiography by Julian Cope
- Head On (Bachman–Turner Overdrive album), 1975
- Head On (Bobby Hutcherson album), 1971
- Head On (Samson album), 1980
- Head On (Super Collider album), 1999
- Head On (Toronto album) or the title song, 1981
- Head On!, an EP by Ausgang, 1984
- "Head On" (song), by the Jesus and Mary Chain, 1989; covered by the Pixies, 1991
- Head On (video game), a 1979 arcade game by Sega
- Head On Photo Festival, an annual photography festival in Sydney, Australia
- Head-on collision, a type of vehicle collision
- HeadOn, a homeopathic product claimed to relieve headaches
- Headon (surname)
- Headon, Nottinghamshire, UK
