Answer
$-2.3\times10^{3}$
Work Step by Step
$320.5-6104.5\div2.3=320.5-2654.1=-2333.6$
For division, the factor with the least number of significant figures determines the significant figures in the result. In this case that number is 2. Since the intermediate result has 2 significant figures the final answer should be written with 2 significant figures.
$-2333.6\approx-2300$
Rewrite -2300 in scientific notation. To express -2300 as a number between 1 and 10 the decimal is moved 3 places to the left so the exponent is 3.
$-2300=-2.3\times10^{3}$