Answer
The transcription factor called MyoD is activated by cell signaling, in turn activating the gene for p21, an inhibitor of the cyclin-dependent kinases that is usually responsible for stimulating the cell cycle at G1. p21 gene expression causes the cell cycle to halt, allowing other transcription factors to help differentiation proceed.
Work Step by Step
The transcription factor called MyoD is activated by cell signaling, in turn activating the gene for p21, an inhibitor of the cyclin-dependent kinases that is usually responsible for stimulating the cell cycle at G1. p21 gene expression causes the cell cycle to halt, allowing other transcription factors to help differentiation proceed.