Chapter 31, Nervous System - Assessment - 31.2 The Central Nervous System - Understand Key Concepts/Think Critically - Page 916: 16

Methamphetamines and cocaine both act on synapses that release dopamine. This is the reason why users feel pleasure when using these drugs, given that dopamine stimulates the reward and pleasure centers of the brain. The difference between them is how they act on the synapse. Methamphetamines cause an excess of dopamine to be released. Cocaine prevents dopamine from leaving the synapse.

Methamphetamines and cocaine both act on synapses that release dopamine. This is the reason why users feel pleasure when using these drugs, given that dopamine stimulates the reward and pleasure centers of the brain. The difference between them is how they act on the synapse. Methamphetamines cause an excess of dopamine to be released. Cocaine prevents dopamine from leaving the synapse.