Answer
Prions cause disease by causing normal PrP proteins in nerve cells to become misfolded. Prions are PrP proteins that have become misfolded. It is the accumulation of these misfolded proteins called prions that causes nerve cells in the brain to malfunction.
Work Step by Step
Prions cause disease by causing normal PrP proteins in nerve cells to become misfolded. Prions are PrP proteins that have become misfolded. It is the accumulation of these misfolded proteins called prions that causes nerve cells in the brain to malfunction.