Answer
If the folding nature of proteins is inflexible and rigid, then certain functions like cell signaling, cell interaction, coordination among cellular activities will get affected.
Work Step by Step
In general, the nature of protein folding is a flexible and spontaneous process. This characteristic folding is essential for the proteins to enable cellular functions like signaling, cell coordination, etc. If it is disordered or misfolded, then controlling cell functions are distorted. Sometimes, misfolding leads to many diseases like Alzheimer's, Cystic fibrosis, etc.
