Answer
A polypeptide for secretion has its signal sequence recognized by the SRP early in translation, at which point its ribosome becomes a bound ribosome on the RER as the protein is cotranslationally inserted into the ER lumen, from where it will travel to the Golgi and to the outside of the cell.
Work Step by Step
This question is connecting the earlier coverage of the cell and its organelles, especially the endomembrane system, with material on gene expression/translation. Review the earlier chapter and use your imagination to see how this chapter has material which fits just before the topic of moving the protein towards the outside of the plasma membrane.
