Answer
$$x=-17$$
Work Step by Step
We solve as follows:
$$8^{x+5}=4^{x-1} \quad \Rightarrow \quad (2^3)^{x+5}=(2^2)^{x-1} \quad \Rightarrow \quad 2^{3x+15}=2^{2x-2} \quad \Rightarrow \quad 3x+15=2x-2 \quad \Rightarrow \quad x=-17$$
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