Answer
-192
Work Step by Step
Multiply the absolute values. Since the number of negative factors is odd the product is negative.
$(-6)(-2)(-4)(-1)(-2)(+2)=-(|-6|\times |-2|\times|-4|\times|-1|\times|-2|\times|+2|)=-(6\times2\times4\times1\times2\times2)=-192$