Answer
$-2\frac{15}{16}.$
Work Step by Step
By unifying the denominators, we have
$$
-\frac{3}{8}+\left(-\frac{1}{4}\right)-2\frac{5}{16}=-\frac{6}{16}-\frac{4}{16}-\frac{37}{16}\\
=\frac{-6-4-37}{16}=-\frac{47}{16}=-2\frac{15}{16}.
$$
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