Answer
$448$
Work Step by Step
The given expression, $
2^3-10[4-3(-2+18)]
$, simplifies to
\begin{array}{l}\require{cancel}
8-10[4-3(16)]
\\\\=
8-10[4-48]
\\\\=
8-10[-44]
\\\\=
8+440
\\\\=
448
.\end{array}
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